Computational & Systems Biology

Computational & Systems Biology

The MIT Computational and Systems Biology Initiative (CSBi) is a campus-wide education and research program that links biologists, computer scientists, and engineers in a multidisciplinary approach to the systematic analysis of complex biological phenomena. CSBi includes about eighty faculty members from over ten academic units across MIT's Schools of Science and Engineering, the Sloan School of Management, and the Whitehead Institute for Biomedical Research.   CSBi places equal emphasis on computational and experimental methods and on molecular and systems views of biological function.   One of CSBi's primary research objectives is the development of methods and devices that can measure, in a systematic and precise manner, the biochemical properties of biomolecules in cells, tissues, and whole organisms. A second CSBi objective is building mathematical models of biological systems that link mechanistic information on molecular function to systems-wide understanding of networks and interactions. Like models in mature fields of engineering, systems biology models will be able to capture empirical information as it accumulates and will have the ability to predict experimental outcomes.