The Broad Institute was founded in 2003 through the extraordinary generosity and vision of philanthropists Eli and Edythe Broad, bringing together the Boston area’s preeminent biomedical research organizations: Harvard University and its affiliated hospitals and MIT. The central mission of the Institute is to transform medicine by using systematic approaches in the biological sciences to dramatically accelerate the understanding and the treatment of disease. Broad scientists pursue a wide variety of projects that cut across scientific disciplines and institutions. Collectively, these projects aim to:
- Build on the Human Genome Project by identifying all of the functional elements of the genome and the variations among humans and other species.
- Gain a complete understanding of the circuits of genomic elements that determine how cells in the body process information and respond to their surroundings.
- Uncover the molecular basis of major inherited diseases through comprehensive studies of genetic variation in human populations.
- Identify all the mutations that underlie different cancer types, thereby laying a foundation for the development of new cancer therapies and diagnostic tools.
- Discover the molecular basis of major infectious diseases in order to develop effective vaccines, rapid diagnostics, and new kinds of therapeutics.
- Transform the process of therapeutic discovery and development to keep pace with biomedical discovery.